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Body composition, hepatic fat, metabolic, and safety outcomes of tesamorelin in HIV-associated lipodystrophy
To be absorbed, a drug given orally must survive encounters with low pH and numerous gastrointestinal (GI) secretions, including potentially degrading enzymes
Results continue improving through month 12, when average losses reach 1522% of starting weight in clinical settings
12-14 In an older study, researchers investigated the absorption and effects of a mucoadhesive, biodegradable buccal GLP-1 tablets in 10 patients with type 2 diabetes